Paul Helquist

Synthesis, structure, and metal complexation behavior of a new type of functionalized chiral phenanthroline derivative.
Journal of Organic Chemistry (2008), 73(10), 3911-3914.

Design and synthesis of a siderophore conjugate as a potent PSMA inhibitor and potential diagnostic agent for prostate cancer.
Bioorganic & Medicinal Chemistry (2008), 16(4), 1648-1657.

Development of a Q2MM force field for the silver(I)-catalyzed hydroamination of alkynes.
Advanced Synthesis & Catalysis (2007), 349(17+18), 2647-2654.

Method of virtual screening of catalyst chiral ligands for prediction of reaction product enantiomeric excess.
PCT Int. Appl. (2007), 37pp.

Total Synthesis of Iejimalide B. An Application of the Shiina Macrolactonization.
Organic Letters (2007), 9(22), 4619-4622.

Process for preparing histone deacetylase inhibitors and intermediates thereof. U.S. (2007), 15pp.

Zinc Binding in HDAC Inhibitors: A DFT Study.
Journal of Organic Chemistry (2007), 72(14), 5446-5449.

Synthesis of carbamate derivatives of iejimalides. Retention of normal antiproliferative activity and localization of binding in cancer cells.
Bioorganic & Medicinal Chemistry (2007), 15(9), 3208-3216.

Development of force field based virtual ligand screening methods for asymmetric, rhodium catalyzed hydrogenations of enamides.
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29, 2007 (2007), ORGN-732.

Application of virtual ligand screening methods for asymmetric, rhodium catalyzed hydrogenations of enamides.
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29, 2007 (2007), ORGN-366.

Synthesis of a 5-azaindole phosphonic acid as a computationally designed inhibitor of the low molecular weight phosphatase HCPTP.
Heterocycles (2006), 70 599-607.

Design, synthesis and pharmacological activity of novel enantiomerically pure phosphonic acid-based NAALADase inhibitors.
Organic & Biomolecular Chemistry (2007), 5(5), 826-831.

Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof.
U.S. Pat. Appl. Publ. (2007), 18pp., Cont.-in-part of U.S. Ser. No. 108,858.

Ligand and Substrate Effects on the Mechanism of Rhodium-Catalyzed Hydrogenation of Enamides.
Journal of Organic Chemistry (2007), 72(3), 839-847.

Mild zinc-promoted Horner-Wadsworth-Emmons reactions of diprotic phosphonate reagents.
Synthesis (2006), (21), 3654-3660.

Development of virtual ligand screening methods for asymmetric, rhodium-catalyzed hydrogenations of enamides.
Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006 (2006), ORGN-063.

 

Posted 07/24/2008